Dr. Matthias EggelAssistent / PostDoc
Assistent / PostDoc
From 2006 to 2010, Matthias Eggel did a Master’s Degree in Human Physiology at the University of Zurich. In his Master Thesis at the University Hospital Zurich, he investigated the effects of ionizing radiation and microtubuli-inhibitors on tumor growth.
From 2011 to 2015, he did PhD in Molecular Biology and Biochemistry at the University of Berne investigating mechanisms of cell competition and their role in organ fitness, aging and cancer in Drosophila Melanogaster.
From 2016 to 2018, Dr. Eggel pursued a PhD in Animal Ethics at the Institute for Biomedical Ethics and History of Medicine at the University of Zurich and the Messerli Research Institute in Vienna, evaluating the benefit concept in animal research and in the authorization of animal research. Since 2019, he works as a Post-Doctoral Fellow and has been teaching Animal Ethics courses for various disciplines (e.g. Life Science, Veterinary and Medical students as well as for transdisciplinary Studies). Matthias Eggel is a Member of the National Ethics Committee in Animal Experimentation of the Swiss Academies of the Arts and Sciences (SAMW) and Member of the Cantonal Animal Research Proposal Review Committee in Fribourg (“kantonale Tierversuchskommission).
His current research focuses on Animal Resarch Ethics and Ethics of Gene Editing. His research interests include:
Animal Research ethics:
- Conceptualization of Harm and Benefit in animal research
- The Ethics of the 3Rs Principle
- Necessity (3Rs), Suitability and Proportionality (Harm-Benefit-Analysis) in animal research
- Ethics of Gene editing in animals, e.g. enhancement and disenhancement
- Regulation of Animal Research
- Ethics of agriculture
- Ethics of veterinary practice
Human germline gene editing
- Furmanova-Hollenstein P, Broggini-Tenzer A, Eggel M, Millard AL, Pruschy M. The microtubule stabilizer patupilone counteracts ionizing radiation-induced matrix metalloproteinase activity and tumor cell invasion. Radiation Oncology. 2013 Apr 30; 8:105.
- Herwig Grimm* und Matthias Eggel*.White Paper and Colourful Language: Toward a Realistic View of Animal Research. ATLA 45, 1–3, 2017, *Authors contributed equally to this work
- Matthias Eggel and Herwig Grimm. The Road to Hell Is Paved with Good Intentions: Why Harm–Benefit Analysis and Its Emphasis on Practical Benefit Jeopardizes the Credibility of Research. Animals
- Matthias Eggel, Anna Deplazes-Zemp, Nikola Biller-Andorno, Herwig Grimm. Necessary, but not sufficient. The benefit concept in the project evaluation of animal research in context of the Directive 2010/63/EU, Animals
- Carolyn Neuhaus*, Matthias Eggel*, Herwig Grimm. Re-evaluating benefits in the moral justification of animal research: A comment on “Necessary Conditions for Morally Responsible Animal Research”. Cambridge quarterly of healthcare ethics. Accepted for publication. *contributed equally to this work
- Katrien Devolder*, Matthias Eggel*. No Pain, No Gain? In Defence of Genetically Disenhancing (Most) Research Animals. Animals 2019. *Authors contributed equally to this work
- Matthias Eggel and Rebecca Walker (2019). REPLACEMENT OR REDUCTION OF GENE-EDITED ANIMALS IN BIOMEDICAL RESEARCH: A COMPARATIVE ETHICS AND POLICY ANALYSIS. North Carolina Law Review
- Springer, S., Dürnberger, C. & Eggel, M. Professional in food chains. Food ethics (2019) 3: 1. https://doi.org/10.1007/s41055-019-00043-7
- MatthiasEggel*and Samuel Camenzind*, Authorization of animal research proposals – a comparison of harm concepts in different European regulations, Berliner undMünchener Tierärztliche Wochenschrift, 2020 (accepted for publication). *Authors contributed equally to this work
- Matthias Eggel and Hanno Würbel, "Internal consistency and compatibility of the 3R and 3V principles for project evaluation of animal research", Laboratory Animals. 2020
- Publications 2021:
- Matthias Eggel, Die Genehmigung von Tierversuchen nach Richtlinie 2010/63/EU – zentrale Konzepte zur Prüfung der „ethischen Vertretbarkeit“, ihre Funktion, praktische Schwierigkeiten und die Beschränkung ihrer „ethischen Reichweite“, in: Mensch – Tier – Gott. Interdisziplinäre Annäherungen an eine christliche Tierethik. Bd. 1 der Reihe: „Interdisziplinäre Tierethik. Interdisciplinary Animal Ethics“, Nomos, 2021.